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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
7.88
Human Site:
S9
Identified Species:
12.38
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S9
A
A
A
E
P
A
S
S
G
Q
Q
A
P
A
G
Chimpanzee
Pan troglodytes
XP_511025
426
45548
A14
L
P
G
R
P
T
D
A
L
L
I
P
P
Q
L
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S9
A
A
A
E
P
A
S
S
G
Q
Q
A
P
P
G
Dog
Lupus familis
XP_853833
304
33793
F9
G
V
K
A
F
V
R
F
R
A
I
V
P
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
S9
A
A
A
E
P
T
S
S
A
Q
P
T
P
Q
A
Rat
Rattus norvegicus
Q62814
300
33206
S9
G
S
S
R
H
E
K
S
L
G
L
L
T
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
Chicken
Gallus gallus
Q90977
403
43534
G32
S
A
S
E
E
P
A
G
G
C
R
P
D
A
D
Frog
Xenopus laevis
NP_001086706
375
40890
V9
A
D
P
A
Q
L
T
V
T
P
S
R
H
E
K
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
P10
E
S
L
Q
P
Q
T
P
S
R
H
E
K
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
N92
S
S
S
D
S
N
S
N
G
G
V
A
A
H
L
Honey Bee
Apis mellifera
XP_624285
300
34327
F9
A
D
N
Q
Q
S
R
F
E
K
S
L
G
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
L26
L
T
T
K
F
V
G
L
L
Q
E
A
P
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
A9
A
A
A
A
G
D
G
A
G
E
A
R
A
R
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
V87
V
D
R
E
E
D
A
V
V
V
R
S
P
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
13.3
93.3
6.6
N.A.
60
6.6
N.A.
0
26.6
6.6
6.6
N.A.
20
6.6
N.A.
26.6
P-Site Similarity:
100
20
93.3
6.6
N.A.
60
20
N.A.
0
53.3
13.3
40
N.A.
53.3
26.6
N.A.
40
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
34
27
20
0
14
14
14
7
7
7
27
14
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
20
0
7
0
14
7
0
0
0
0
0
7
7
7
% D
% Glu:
7
0
0
34
14
7
0
0
7
7
7
7
0
7
0
% E
% Phe:
0
0
0
0
14
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
14
0
7
0
7
0
14
7
34
14
0
0
7
0
20
% G
% His:
0
0
0
0
7
0
0
0
0
0
7
0
7
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% I
% Lys:
0
0
7
7
0
0
7
0
0
7
0
0
7
7
14
% K
% Leu:
14
0
7
0
0
7
0
7
20
7
7
14
0
7
27
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
0
34
7
0
7
0
7
7
14
47
7
0
% P
% Gln:
0
0
0
14
14
7
0
0
0
27
14
0
0
14
7
% Q
% Arg:
0
0
7
14
0
0
14
0
7
7
14
14
0
7
7
% R
% Ser:
14
20
20
0
7
7
27
27
7
0
14
7
0
14
0
% S
% Thr:
0
7
7
0
0
14
14
0
7
0
0
7
7
7
0
% T
% Val:
7
7
0
0
0
14
0
14
7
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _